I'm surprised no one mentioned THE CLASSIC paper on this topic with respect
to evolution. This paper is required reading in most molecular evolution
graduate courses -- or at least should be. The paper:
Kacer and Burns. 1981. The molecular basis of dominance. Genetics 97:
639-666.
The paper describes how mutant alleles in an enzyme pathway will
automatically be recessive in nature wholly as a result of the kinetic
properties of enzyme flux.
Tony Long
Center for Population Biology
U. C. Davis
Davis, CA
tdlong at ucdavis.edu
