Tony Long (tdlong at ucdavis.edu) wrote:
: I'm surprised no one mentioned THE CLASSIC paper on this topic with respect
: to evolution. This paper is required reading in most molecular evolution
: graduate courses -- or at least should be. The paper:
: Kacer and Burns. 1981. The molecular basis of dominance. Genetics 97:
: 639-666.
: The paper describes how mutant alleles in an enzyme pathway will
: automatically be recessive in nature wholly as a result of the kinetic
: properties of enzyme flux.
: Tony Long
: Center for Population Biology
: U. C. Davis
: Davis, CA
:tdlong at ucdavis.edu
BUT, the UR_CLASSIC is Wright, S. 1934. Physiological and evolutionary
theories of dominance. Amer. Nat. 68:25-53.
Kacser & Burns is derivative.
