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Dominance mechanisms - molecular

Sat Mar 26 16:26:48 EST 1994

In article <Cn6t5x.9zD at ucdavis.edu>, john at josquin.ucdavis.edu (John Gillespie)

>Tony Long (tdlong at ucdavis.edu) wrote:
>: I'm surprised no one mentioned THE CLASSIC paper on this topic with respect
>: to evolution.  This paper is required reading in most molecular evolution
>: graduate courses -- or at least should be.  The paper:
>: Kacserand Burns.  1981.  The molecular basis of dominance.  Genetics 97:
>: 639-666.

>BUT, the UR_CLASSIC is Wright, S. 1934. Physiological and evolutionary
>theories of dominance.  Amer. Nat. 68:25-53.
>Kacser & Burns is derivative.

   Actually to my reading of the literature Wright (1934) is derivative of
earlier works by Haldane and Muller. A review of this may be found in a paper
which is in press:

  "The Heat-Shock Response and the Molecular Basis of Genetic Dominance"
   J. Theoretical Biology. vol 167. (1994).

                    Sincerely,  Don Forsdyke

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