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I am interested in finding all examples where HUMAN cDNAs can complement
yeast (S. cerevisiae) mutations. Below are those that I have found so far.
Please write back ASAP with any that you might know of that I missed.
Please include references if available.
Thanks,
Stuart T.
YEAST MUTANT Human gene
cdc9 DNA ligase I
hap2 human hap2
vdac HVDAC1 and 2
rbp1 hFKB12
srm1/prp20 RCC1 (rescues ts, not null)
pro3 P5C reductase
cdc28 P34CDC2
cdc28 CDK2
cdc28 CDK3
nmt1 NMT (rescues ts or null)
cpr1 oxidoreductase
cim5 MSS1
pfk? Phosphofructokinase, muscle
cki1 choline kinase
gst1 GST1-Hs or GSPT1
nop1 fibrillarin
rad6 HHR6A, HHR6B
arf1 /arf2 ARF5 or ARF6
gal1 galactokinase
cdc24 p21rap1A
cdc42-1 or cdc24-4 G25K
pde1,2 HCP1
ura1 dihydroorotate dehydrogenase
abf2 MTTF1
cdc34 HUMCDC34H
cks1 CKShs1 or CKShs2
smd1 snRNP D1
ade5, 7, or 8 GART
cdc8 dTMP kinase
cyc1 cytochrome c
glc3 HGBE
cln1,2,&3 Cyclin D1/PRAD1/CCND1