It seems to be taken as given in the literature discussing nucleotide
sequence mutagenesis, that transition mutations generally predominate over
tranversions. What I have missed in all the papers that take this as an
axiom is any reference to a publication that rigorously examined this
question. Can anyone point me to such a reference? Is there sufficient
evidence to conclude that transitions do predominate over transversions, or
were these conclusions reached (and then taken as gospel) by analysis of a
much too limited dataset?
Elliot
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* Elliot J. Lefkowitz, Ph.D. *
* University of Alabama *
* Biological Computing Resource Facility *
* Department of Microbiology *
* Birmingham, AL 35294-2170 *
* *
* Lefkowitz at orion.cmc.uab.edu *
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