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Nobel Price discovery?

Keith Robison robison at lipid.harvard.edu
Tue Oct 18 10:00:23 EST 1994

Jan Ulrik Thorup (thorup at BIOBASE.AAU.DK) wrote:

: Dear netters!

: Has anyone ever before experimentally seen that through evolution two exons 
: merged to one exon, say that a intron through evolution has dissappeared ?

This is a point of some controversy, but yes, there are probably lots
of good examples of this occurring, though it is probably rare to
catch it in two closely related species (unless one gene lost all of
its introns via retrotransposition).  I suggest you look at the large
body of information (and arguments) on exons and evolution generated
by Walter Gilbert, Jeff Palmer, Russell Doolittle, Ford Doolittle,
Laslo Patthy, et al.  

Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison at mito.harvard.edu 


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