The best estimate of the intrinsic Ts/Tv rate is probably that
determined by comparison of the most closely related sequences
you have. The more distant the sequences, the more this rate
is randomized.
gg
*****************************************************************
* George A. Gutman *
* Department of Microbiology Tel:(714)824-6593 *
* and Molecular Genetics FAX:(714)824-8598 *
* University of California INTERNET: GAGUTMAN at UCI.EDU *
* Irvine CA 92717 *
*****************************************************************
