Announcement: Tree reconstruction with Puzzle 2.1

[Korbinian Strimmer]

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                       A N N O U N C E M E N T
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    Puzzle version 2.1 is now available on the anonymous ftp site
    fx.zi.biologie.uni-muenchen.de (141.84.243.45).
    
    Documentation, ANSI C code with UNIX Makefile, and Mac and
    PowerMac executables are located at /pub/puzzle.



PUZZLE:

Puzzle is a PHYLIP compatible program that implements the quartet
puzzling method for reconstructing tree topologies from nucleic
and protein sequence data. 

Quartet puzzling is a method that applies maximum likelihood tree
reconstruction to all possible quartets and subsequently tries to
combine most of the four-species maximum likelihood trees to construct
an overall tree.  Usually there are several equally good solutions.
A consensus tree generated from the quartet puzzling trees shows which
nodes are well supported.  More details will be published elsewhere.


VERSION HISTORY:

Quartet puzzling was presented at the phylogenetic workshop 1995 in
Bielefeld, Germany, where Puzzle version 1.0 was distributed.
Puzzle version 2.0 was a completely rewritten version of Puzzle 1.0
merging the maximum likelihood program and the quartet puzzling program
into one user friendly program.  Puzzle 2.0 was distributed
electronically.
Puzzle 2.1 implements a slightly improved quartet puzzling algorithm.
The meaning of the transition/transversion parameter is now to that
in PHYLIP DNAML (was identical to MOLPHY NucML).
Some minor bugs are fixed.


CORRESPONDENCE:

Arndt von Haeseler
Korbinian Strimmer

Zoologisches Institut
Universitaet Muenchen
Luisenstrasse 14
D-80333 Muenchen
Germany.

Phone: +49-89-5902327
Fax:   +49-89-5902474

arndt at zi.biologie.uni-muenchen.de
strimmer at zi.biologie.uni-muenchen.de