A N N O U N C E M E N T
Puzzle version 2.1 is now available on the anonymous ftp site
Documentation, ANSI C code with UNIX Makefile, and Mac and
PowerMac executables are located at /pub/puzzle.
Puzzle is a PHYLIP compatible program that implements the quartet
puzzling method for reconstructing tree topologies from nucleic
and protein sequence data.
Quartet puzzling is a method that applies maximum likelihood tree
reconstruction to all possible quartets and subsequently tries to
combine most of the four-species maximum likelihood trees to construct
an overall tree. Usually there are several equally good solutions.
A consensus tree generated from the quartet puzzling trees shows which
nodes are well supported. More details will be published elsewhere.
Quartet puzzling was presented at the phylogenetic workshop 1995 in
Bielefeld, Germany, where Puzzle version 1.0 was distributed.
Puzzle version 2.0 was a completely rewritten version of Puzzle 1.0
merging the maximum likelihood program and the quartet puzzling program
into one user friendly program. Puzzle 2.0 was distributed
Puzzle 2.1 implements a slightly improved quartet puzzling algorithm.
The meaning of the transition/transversion parameter is now to that
in PHYLIP DNAML (was identical to MOLPHY NucML).
Some minor bugs are fixed.
Arndt von Haeseler
arndt at zi.biologie.uni-muenchen.destrimmer at zi.biologie.uni-muenchen.de