In article <carmean-1512951828090001 at berbee.botany.ubc.ca>, carmean at sfu.ca
(Dave Carmean) wrote:
...
> I find it interesting that there is no discussion here of using homology
> (such as secondary structure) to align sequences. Karl Kjer has been
> working on this aspect of alignment.
You mean: bottom up - top down:first spend a linear amount of time by
calculating the conformation of a certain structure (from bottom up), then
match these structures by shape and finally doing a more precise alignment
(top down)
interesting. Where can we find more information? (references?)
ard
