Sequence data and cladistics

Agneta Guillemot Agneta.Guillemot at historia.umu.se
Tue May 9 18:58:14 EST 1995

I have a question to systematicists concerning  
molecular sequences and it's application in  
cladistic analyses. The question is as follows: 
Has anyone ever been able to prove anything in  
a true cladistic analysis with sequence data  
from proteins or DNA? I'm not interested in talk  
about molecular clocks and what they are presumed  
to have proved concerning the relationships of  
different taxa, only in true cladistics. What  
I want to see with my own eyes are unique sequences  
in DNA or proteins (not single substitutions of  
an amino acid or a base pair) shared by the taxa  
you want group together, while the other candidates  
for inclusion into this group have the primitive  
sequence as determined by outgroup comparison. To  
you who knows anything about this, please include in  
your reply to this forum (if it's not to much work) 
a short list of articles or data bases where I can  
find such data as described above.  
If you belive that the genom of an organism ultimatly 
controls the sequences of all proteins, and therefore 
the signals that determines what an organism is, and  
you also have a basic grasp of cladistics (and of course 
belives in evolution) you must also belive that sequence 
data from proteins and DNA can be used in a cladistic 
analysis. "shared derived sequences" must exist. The 
tricky business is to find them among the billions of  
base pairs in a genom. 
Have they been found? I want to know! 
Thank you for your attention! 
Ludvig Mortberg  
Umea, Sweden 

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