In article <3pae4j$pnv at mserv1.dl.ac.uk>, gsteiner at zoo.univie.ac.at. wrote:
> Can anyone in this forum explain the principles of "spectral
> analysis" of sequence data? Is there any biological significance in
> this method?
>> Hoping for most enlightening replies!
>> Gerhard
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> X Dr. Gerhard Steiner X X==========================X
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>>
Hi Gerhard!
The clearest example of its application to date is by Lento, Hickson,
Chambers, and Penny (MBE 12:28-52. 1995.) I suggest that you particularly
study Figure 3 in that article. Note also that a LogDet (log determinant)
transformation of the data does an amazing job of increasing the
frequency of pairwise comparisons that support a particular
hypothesis. Sorry this is not much of an explanation of the method
but I'm not sure I could do that in 30 words or less.
Doug
--
Doug Eernisse <DEernisse at fullerton.edu>
Dept. Biological Science MH282
California State University
Fullerton, CA 92634
