Randy Zauhar (zauhar at xhost5.tripos.com) wrote:
: Keith Robison wrote:
: >There really isn't much reason _a priori_ to expect recombination from
: >occuring amidst a codon. Remember, the bulk of recombination involves
: >exact pairing between two pieces of DNA coding for about the same
: >thing, and so there are unlikely to be harmful effects from
: >the recombination event (i.e. recombination is unlikely to generate
: >a frameshift from two unframeshifted genes).
: Sorry if this should be "common knowledge", but what is the probability
: of introducing a frameshift during crossover? I have wondered about this,
: but have never run across any estimates. I wonder if it is an effect that
: can even be measured apart from other factors that introduce frameshifts?
Because pairing is almost always precise, frameshifts are almost
never introduced. I don't know if anyone has really measured
it.
Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI
robison at mito.harvard.edu
