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DNA substitutions saturated?

Joe Felsenstein joe at evolution.genetics.washington.edu
Wed Nov 29 18:20:10 EST 1995

In article <carmean-2911951219520001 at berbee.botany.ubc.ca>,
Dave Carmean <carmean at sfu.ca> wrote:
>Any suggestions for the best (and hopefully simplest) way to discover if
>the substitutions in my DNA alignment are saturated?
>I can use DNAdist (PHYLIP) to find the rates of substitution between taxa
>and Hillis's g1 test to indicate that the data set is not random.  Neither
>of these directly address the question of saturation.

Wouldn't being _really_ saturated be the same as looking like a random and
unrelated sequence?  If so, your test rejecting randomness would already have
rejected true saturation.

Joe Felsenstein         joe at genetics.washington.edu     (IP No.
 Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA

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