Postdoctoral position in molecular evolution in laboratory of Barry G. Hall.
The Sloan Foundation and NSF have announced joint funding of postdoctoral
fellowships in molecular evolution . I am interested in sponsoring an applicant
to conduct research on Adaptive (also called "directed", "selection-induced", or
"Cairnsian") Mutations in E. coli. Adaptive mutations occur by mechanisms
different from the mechanisms that give rise to random, growth-dependent
mutations; occur in non-dividing or extremely slowly dividing cells; and appear
to consist exclusively of "useful" mutations that allow cells to resume rapid
growth. I am interested both in testing existing models for the mechanisms to
account for adaptive mutagenesis, in constructing and testing additional models,
and in studying the roles of adaptive mutations in evolutionary processes.
See:
Hall, B.G. 1994 Selection or mutation: Which, if either, comes first? FEMS
Microbiol. Lett. 117: 237-242.
Hall, B.G. 1995 Genetics of selection-induced mutations: I. uvrA, uvrB, uvrC,
and uvrD are selection-induced specific mutator loci. J. Mol. Evol. 40: 86-93.
Hall, B.G. 1995 Adaptive mutations in Escherichia coli as a model for the
multiple mutational origin of tumors. Proc. Nat. Acad. Sci. USA 92:
5669-5673.
Candidates must have received the Ph.D. degree after January 1, 1991 or
anticipate receiving that degree before June 30, 1996. The fellowship pays a
stipend $28,000 per year, includes a $8000 allowance for supplies and travel,
and has a possible start date between July 1, 1996 and January 1, 1997.
Interested applicants should contact me prior to October 1, 1995 in order to
complete the necessary application by the submission deadline of November 1,
1995.
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Barry G. Hall PHONE: (716) 275-0721
Biology Department FAX: (716) 275-2070
River Campus E-Mail: Bhall at bgh.biology.rochester.edu
University of Rochester
Rochester, NY 14627
