In article <01HV2R1MTH4I8Y665K at gnv.ifas.ufl.edu>, CAMP at GNV.IFAS.UFL.EDU (Don Campton) writes:
> Dear colleagues,
> Please suggest references (original research papers, reviews, etc.)
> documenting the integration of mtDNA genes or sequences (e.g. D-loop)
> into the nuclear genome, especially of vertebrates. I am referring to
> potential instances where the same or similar sequence (perhaps the
> entire 16kb homologous sequence) occurs in both genomes. This
> obviously would create PCR problems if one did not do a cell fractionation
> step or CsCl separation of the two genomes prior to amplification. Your
> help will be appreciated. Thanks.
> Don Campton
> Department of Fisheries and Aquatic Sciences
> University of Florida
Hi Don:
sorry for the delay in replying. Steven J. O'Brien and colleagues
have found half of a mitochondrial genome integrated into the nuclear
genome of some cats (felidae). It looks like it is behaving like a big
pseudogene and they have found no transcripts from it.
I have no references to this stuff I am afraid.
Des
