This announcement is being cross-posted to several newsgroups.
Please, excuse the duplication.
Dear All,
The following paper is now available as ZIP-compressed
PostScript file via anonymous ftp from:
ftp://ftp.iephb.ru/pub/spirov/selfassembl.zip
and as HTM(L) Pages:
URL: http://www.iephb.ru/selfass0.html
URL: http://avs.iephb.ru/selfass0.htm
Interactively:
ftp ftp.iephb.ru
login: anonymous
Password: <your_e-mail_address>
cd pub/spirov
binary
get selfassembl.zip
quit
The pub/spirov/index file contains an index of the other files.
These materials are submitted for THE FOURTH INTERNATIONAL CONFERENCE ON
PARALLEL PROBLEM SOLVING FROM NATURE (PPSN IV)
BERLIN, SEPT., 1996. Any comments and criticisms are
most welcome.
Title: "SELF-ASSEMBLAGE OF GENE NETS IN EVOLUTION VIA
RECRUITING OF NEW NETTERS "
Author: Alexander V. Spirov
ABSTRACT
To understand the conditions under which mutations and selection can lead
to rising level of organization is of importance for evolutionary biology
as well as in evolutionary computations. It is well-known that biological
morphogenesis is the result of a cooperative self-regulating,
self-organizing processes that is controlled by the genome. That is why
many of the new developments of GA's begin to use hybrid systems which
model both the self-organizing and selective mechanisms of biological
systems.
What is more, we must take into consideration two aspects of the
self-organisation mechanisms in evolution. First aspect has been working
out by some authors and deals with self-organising mechanisms of the
genotype-phenotype presentation. Second aspect will be discussed here.
According to it, self-organization become apparent in evolution as
self-assemblage of the gene networks and cascades.
This paper describes our first steps toward a biologically defensible model
of evolutionary growth of Drosophila segmentation gene network. The
identification of controller genes has been a significant recent finding in
developmental biology. Networks and cascades of controller genes serve to
orchestrate expression of the genome during embryo development. We use
up-date knowledge about structure, function and evolution of real gene
networks for the purposes of computer simulation of the networks
self-organization in evolution. Our computer simulations of evolution of
gene networks governing the embryo morphogenesis show possibility for
self-organization or self-assemblage (or "outgrowth") of the networks. This
self-assemblage proceeds by means of recruiting of new genes via closing up
of new functional circuits between new and old members of the network.
KEYWORDS: self-organisation, evolution, genetic algorithms,
genotype-phenotype presentation, gene networks, artificial life,
evolutionary biology.
(13 pages, 13 color illus.)
PS: The PS-file was generated by WinWord 7 and tested
by GhostScript viewer for Windows.
Alexander V.Spirov (PhD)
I.M.Sechenov Institute of Evolutionary Physiology &
Biochemistry, S.-Petersburg, Russia
phone/fax +7 (812)552 3219; fax + 7 (812)552-3012
WWW http://avs.iephb.ruSpirov at iephb.ru
