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% GC content and 16S phylogeny

Martijn Huynen mah at santafe.edu
Tue Aug 6 16:49:19 EST 1996

Jeffrey Lawrence wrote:
> yes it is.  consult muto and osawa (1987) PNAS 84:166 (not completely
> sure about page number)
> while GC content of structural RNA genes is positively correlated
> with GC content of the genome, much stronger relationships, in
> terms of the degree of variation, are found in first and third
> codon positions.
One reference is:
        author =        {Jacob Z. Dalgaard and Roger A. Garrett},
        title =         {Archaeal hyperthermophile genes.},
        booktitle =          {The Biochemistry of Archaea},
        editor =        {A. Neuberger and L.L.M. van Deenen},
        pages =         {535-536},
        year =          {1993},
        publisher =        {Elsevier},
        address =        {Amsterdam},

It shows that the G+C content of the ribosomal RNA is in general
correlated with the environmental temperature, whereas the 
G+C content of the entire genome is not.

Best, Martijn Huynen

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