I am interested in codon bias as a combinatorial optimization
problem...in some organisms, "optimal" codon usage appears to be
correlated with the level of gene expression--highly expressed genes use
the optimal codons whereas genes with lower expression use rare codons.
Essentially, I am interested if this pattern results from a complex
optimization process?
Does anyone know of any articles on this issue?
Thanks in Advance
Jeff
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Jeff Huckaby Jeff Huckaby
Department of Biology 420 OML
email huckabyj at minerva.cis.yale.edu Yale University
office:(203) 432-3877 New Haven, CT 06511
WWW http://www.yale.edu/~huckabyj/topbio.html Lab:(203) 432-3982
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