Codon Bias

Jeffrey J. Huckaby huckabyj at minerva.cis.yale.edu
Wed Feb 7 10:25:18 EST 1996

	I am interested in codon bias as a combinatorial optimization 
problem...in some organisms, "optimal" codon usage appears to be 
correlated with the level of gene expression--highly expressed genes use 
the optimal codons whereas genes with lower expression use rare codons.  
Essentially, I am interested if this pattern results from a complex 
optimization process?

	Does anyone know of any articles on this issue?
Thanks in Advance

Jeff Huckaby                                                      Jeff Huckaby
Department of Biology						       420 OML
email huckabyj at minerva.cis.yale.edu                            Yale University
office:(203) 432-3877               		  	   New Haven, CT 06511
WWW http://www.yale.edu/~huckabyj/topbio.html     	    Lab:(203) 432-3982

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