IUBio

gamma distribution/PHYLIP

Nicolas Chalwatzis, MIPS CHALWATZIS at MIPS1.dnet.mips.biochem.mpg.de
Wed Feb 21 11:28:42 EST 1996


Dear Netters,

- the program DNADIST of the PHYLIP package has the option to calculate 
  sequence distances based on a gamma-distribution (Jin and Nei 1990). 
  However, the program requires the "Coefficient of variation of substitution 
  rate among sites (must be positive)"  -  What's the best way to evaluate 
  this coefficient for a given dataset (sequence alignment) ?

Best wishes and many thanks in advance,

Nico Chalwatzis

e-mail: chalwatzis at mips.embnet.org




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