- the program DNADIST of the PHYLIP package has the option to calculate
sequence distances based on a gamma-distribution (Jin and Nei 1990).
However, the program requires the "Coefficient of variation of substitution
rate among sites (must be positive)" - What's the best way to evaluate
this coefficient for a given dataset (sequence alignment) ?
Best wishes and many thanks in advance,
e-mail: chalwatzis at mips.embnet.org