Many of us spend our days (and nights!) cloning, expressing and/or
knocking out genes that interest us. Often times, however, we are too
deep in the trees and lose sight of what our gene's function is in the
context of a whole animal or even at the organ level. I would be
interested to know what level of enthusiasm there is out there for
studying the physiology of your favorite gene. If you are overexpressing
a transcription factor that regulates cardiac gene expression, for
example, what effect does this have on cardiac performance, blood
Granting agencies are asking for more than molecular biology these days;
they want relevance to a physiological or pathophysiological process.
Within this context, would you be interested in learning physiology
techniques (blood pressure measurements, cardiac and smooth contractility,
shear stress, electrophysiology etc) in a 2-3 week course as a means of
broadening your knowledge base and enhancing your experimental research??
Please forward your thoughts and comments to jmiano at post.its.mcw.edu.
Thanks in advance!
Joe Miano & David W. Stepp