Many of us spend our days (and nights!) cloning, expressing and/or
knocking out genes that interest us. Often times, however, we are too
deep in the trees and lose sight of what our gene's function is in the
context of a whole animal or even at the organ level. I would be
interested to know what level of enthusiasm there is out there for
studying the physiology of your favorite gene. If you are overexpressing
a transcription factor that regulates cardiac gene expression, for
example, what effect does this have on cardiac performance, blood
pressure etc.?
Granting agencies are asking for more than molecular biology these days;
they want relevance to a physiological or pathophysiological process.
Within this context, would you be interested in learning physiology
techniques (blood pressure measurements, cardiac and smooth contractility,
shear stress, electrophysiology etc) in a 2-3 week course as a means of
broadening your knowledge base and enhancing your experimental research??
Please forward your thoughts and comments to jmiano at post.its.mcw.edu.
Thanks in advance!
Joe Miano & David W. Stepp
