IUBio

GC content and phylogeny reconstruction

Jonathan F. Wendel jfw at iastate.edu
Wed Nov 13 23:10:14 EST 1996


A paper was recently published in which it was demonstrated that in 
phylogenetic analysis, a potentially misleading resolution could be 
obtained in cases where the sampled genes varied greatly in their GC 
content.  The conclusion was, as I recall, that "high-GC" genes were 
spuriously linked by virtue of this compositional bias by itself.  I'm 
going crazy trying to recall what this reference was..... can anyone 
help?

Thanks, Jonathan Wendel



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