To: molecular-evolution at dl.ac.uk
From: eroshkin at vector.nsk.su <Alexey Eroshkin>
Subject: Protein Multiple Sequences Editor on IuBio FTP-server
ProMSED, Protein Multiple Sequences EDitor for MS Win 3.x/95
is available now from IuBIO software library:
(as self-extracted archive).
ProMSED is an easy-to-use application for automatic
and manual multiple protein sequences alignment, alignment editing,
analysis and printing. Interface and the main functions are similar to
Microsoft Word. ProMSED can align complete set of sequences, its subset
and any selected block, providing thus flexible tool for sequences
analysis, visualization, edition and illustrations preparation.
o reads five sequence formats (NBRF/PIR, Pearson (Fasta),
EMBL/SwissProt, Intelligenetics and CLUSTAL) and combines sequences
from different files;
o automatic multiple sequence alignment with ClustalV algorithm;
o single and multiple sequence input and edit;
o manual alignment includes sequences grouping, blocks deleting,
o visual analysis is facilitated by amino amino acid coloring reflecting
aa similarity in physico-chemical, mutational and other properties;
o option for interactive alignment in selected block, leaving unchanged
previously aligned regions;
o outputs alignment in two formats, produces publication quality
o loads several protein families into different windows;
o a HELP is included.
Special thanks to Dr. Desmond Higgins for source code of ClustalV.
Demo version has limits on length and number of sequences.
Comments, bug reports and suggestions for new features are welcome and
should be sent by email to eroshkin at vector.nsk.su. Inquiries can be
Dr. Alexey Eroshkin Institute of Molecular Biology
E.mail: eroshkin at vector.nsk.su State Research Center of Virology and
Tel: +7 (3832) - 647774 Biotechnology "Vector"
Fax: +7 (3832) - 328831 Koltsovo, Novosibirsk Region 633159