IUBio

what is alive - prions

Mike O'Hara mohara at ihug.co.nz
Sat Sep 21 09:48:15 EST 1996


Martiijn Huynen wrote (paraphrasing) that as far as he knew prions did 
not adapt

I'm not sure that IS true. The situation with the current BSE agent in 
the UK is still not clear but if the people who have died of 
Creutzfeld-Jacob did get it from infected beef then they are a lot 
younger than other cases to date. My proviso here is that there may have 
been cases in the pat not identified as CJD. 

Be that as it may, there is some hints that the agent in question, which 
appears to have come from sheep, has adapted its host range and its 
ability to catalyse change in normal PrP. sounds fairly alive to me..

I accept that some of this is hypothesis, the prooblem with 'slow 
virus' diseases is modelling behaviour.

Mike O'Hara




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