Etiology of Male Homosexuality and Current Rise

James Howard jmhoward at sprynet.com
Wed Aug 27 15:35:26 EST 1997

Etiology of Male Homosexuality and Current Rise of Male Homosexuality
James Howard

In 1985, I developed an hypothesis (copyrighted) of male homosexuality 
that produced predictions.  These predictions have since been supported. 
 My explanation is very lengthy; for sake of brevity I am including the 
significant part regarding the predictions.  As you read this, you 
should know that, earlier in my treatise, I said this: "As I have 
suggested, DHEA is directly responsible for growth and differentiation 
of the brain." In the context of homosexuality, I was saying that 
reduced DHEA will reduce growth of specific areas of the brain that 
determine sexuality.  In the fetus, the ratio of DHEA to estrone, which 
I mention in the following quotation, is determined by the mother, as 
the adrenal glands of the fetus do not function until birth.  ("Results 
indicate that the fetal adrenal activity increases independently of the 
maternal adrenal cortex at term and plays an important role in the onset 
of labour." Orv Hetil 1987; 128: 2153).

"Not all human fetuses are exposed to molecules of the type that I have 
been discussing.  I propose that the hormone which induces homosexuality 
in humans is estrone.  This hormone could induce alterations in critical 
function of the receptors during critical periods.  Estrone is only one 
conversion step away from DHEA in the enzymatic syntheses in the adrenal 
glands.  Remember that DHEA sulfate is the chief precursor molecule of 
estrone.  [Here I meant the mother.]  During the genesis of the nervous 
system, a ratio of DHEA/estrone might occur abnormally in the fetus.  
This would continue throughout life.  The amount of DHEA/estrone would 
determine the degree of influence from slight to the syndrome of 
homosexuality."  To further clarify this, later in my treatise, I 
suggested:  "It is important to differentiate here between the asexual 
male and the homosexual.  The person of low DHEA without estrone 
production, might very well become asexual."

For this argument I want to demonstrate that a number of these 
predictions have been supported, subsequent to 1985.  The effects of 
DHEA on growth and differentiation of neurons was reported in 1987.  

"In the present study, using methods of immunocytochemistry, 
autoradiography, and scanning electron microscopy, we show that a 
supplement of as little as 10(-8) M DHEA or DHEA-S greatly increases 
neuronal survival and differentiation and reduces astroglial 
proliferation rates in mouse brain cells in cultures." J Neurosci Res 

In 1992, a study of homosexual men, during progressive stages of AIDS, 
determined that DHEA is low and estrone high.  As you read the following 
quotation, notice the use of the word "all."  "The serum DHEA sulfate 
values of all groups of HIV+ patients were lower than those of controls. 
The serum E1 [estrone] and E2 [estradiol] were elevated 30-50% 
(p<0.01) in all groups of HIV+ patients." J Acquired Immune Deficiency 
Syndromes 1992; 5: 841.

So, I suggest that male homosexuality results, in utero, from an 
increased ratio of estrone to DHEA.  This combination results in the 
increased growth, and reduced growth of other structures, in the male 
homosexual brain.  Furthermore, my hypothesis can be extended to explain 
the current rise in homosexuality.  While I think the current "climate" 
of increased acceptance of homosexuality may account for more 
acknowledging their homosexuality, I think the current increase is due 
to an evolutionary phenomenon.

My theory of human evolution suggests that testosterone is currently 
rising.  I suggest testosterone periodically rises in civilizations, and 
this increased testosterone causes a number of phenomena, including an 
increase in homosexuality.  If you understood my explanation of 
increases in estrone in the mother as the cause of male homosexuality, 
then some connection of testosterone and estrone should exist.  This has 
been confirmed.  In the following report, a positive correlation was 
found between testosterone and "unconjugated and total estrone."

"Serum androgens, estrogens, 'steroid-sensitive proteins', thyroid 
components, and albumin were measured twice within a 4-5 week interval 
in 44 cases of early normal pregnancy (gestational weeks 8-18). Positive 
correlations were found in the total material between 
dehydroepiandrosterone sulfate (DHAS) and testosterone (T), unconjugated 
and total estrone, albumin, tetraiodothyronine, and calculated free 
tetraiodothyronine concentrations and within 2-week intervals between 
DHAS and T, estradiol-17 beta, and unconjugated and total estrone, and 
between T and estradiol-17 beta and unconjugated estrone." Gynecol 
Obstet Invest 1995;40(3):145-150

I suggest that the current rise in male homosexuality is the result of 
increased testosterone in women.  It is known that the phenomenon known 
as the "secular trend" is occurring here.  The secular trend is 
characterized by increased size in our children, male and female, and an 
earlier onset of puberty.  I suggest the secular trend is driven by 
increased testosterone and the rise in male homosexuality is a result of 

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