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What is the most common genetic abnormally?

Joe Felsenstein joe at evolution.genetics.washington.edu
Mon Jun 16 00:49:48 EST 1997

In article <5o1kl5$b4k at dfw-ixnews12.ix.netcom.com>,
Steven B. Harris <sbharris at ix.netcom.com> wrote:
>In <33A367BC.4B7E at sprynet.com.ns> Elliot Williams
><kakapo at sprynet.com.ns> writes: 
>>What is the most common genetic abnormally?
>   About 1 in 20 carries the gene for cystic fibrosis, with the
>homozygous frequency being about 1 in 4*(20)^2 = 1600.

How about lactose intolerance, which is highly frequent in non-European
populations, and I think about 15% of Europeans are homozygotes for it?
Me, I'm a heterozygote ...

Joe Felsenstein         joe at genetics.washington.edu     (IP No.
 Dept. of Genetics, Univ. of Washington, Box 357360, Seattle, WA 98195-7360 USA

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