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What is the most common genetic abnormally?

HH Awareness c845a at geocities.com
Wed Jun 18 23:17:58 EST 1997

Re: What is the most commom genetic abnormally?

In some cases, such as sickle anemia, the heterozygote (single
gene) may have a selective advantage in a certain population
(i.e. greater resistance to malaria) and is therefore selected
for. Whereas the homozygote (double gene)  is likely to die

Does anybody know of a selective advantage of being heterozygous
for hemochromatosis or cystic fibrosis? 

If you do not know what hemochromatosis (iron overload) is,
please visit http://www.emi.net/~iron_iod/ and spread the word.

E. Williams, HH Awareness, http://www.geocities.com/HotSprings/5686

Steven B. Harris wrote:
> In <33A367BC.4B7E at sprynet.com.ns> Elliot Williams
> <kakapo at sprynet.com.ns> writes:
> >
> >What is the most common genetic abnormally?
> >
> >Is hemochromatosis (iron overload) the most common genetic
> >abnormally?
> >
> >Heterozygous (single gene) 1 in 8
> >Homozygous (double gene) 1 in 200
> >(source: http://www.emi.net/~iron_iod/io42000.html).
> >
> >What are the other common genetic abnormalities?
> >
> >E. Williams
> >kakapo at sprynet.com
> >
>    About 1 in 20 carries the gene for cystic fibrosis, with the
> homozygous frequency being about 1 in 4*(20)^2 = 1600.  Of course, the
> frequency of these things varies with the population.
>                           Steve Harris, M.D.

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