I discuss the case of hemoglobin from this point of view in:
Gordon, R. (1994). Evolution escapes rugged fitness landscapes by gene or
genome doubling: the blessing of higher dimensionality. Computers &
Chemistry 18(3), 325-332.
Best, -Dick Gordon
>I would like to know if there is any known correlation between enzymatic
>activity and evolution; i.e. if the activity of a given enzyme (its
>Kcat.)varies in the different organisms in a way that has something to
>do with their
> If the answer is yes, do you have any references on this subject?
> Please, reply (also) to my e-mail address, since I do not usually read
> Thanks a lot in advance,
>> Lorenzo Stella
>Stella at stc.uniroma2.it Fax ++39-06-72594328 Tel ++39-06-72594463
>"When you have excluded the impossible, whatever remains, however
>improbable, must be the truth." (S. Holmes)
Dr. Richard Gordon, Radiology, U. Manitoba, HSC, 820 Sherbrook Street,
Winnipeg R3A 1R9 Canada, Phone: (204) 789-3828, fax: (204) 787-2080/ Book
just out: The Hierarchical Genome & Differentiation Waves: Novel
Unification of Development, Genetics & Evolution:
GordonR at cc.UManitoba.ca (Adjunct: Electrical & Computer Engineering), Exec
Member: CSTB, CARRF, IEEE-EMBS.