Persistence of separate mitochondrial genome

Holger Hupfer hupfer at botanik.biologie.uni-muenchen.de
Wed Sep 13 02:18:12 EST 2000

Andrew Gyles schrieb:

> At a conference in Italy in 1994 Saccone et al said, 'The fundamental
> question..."why mtDNA and a separated organellar genetic system should
> have persisted throughout evolution?" is still waiting for a convincing
> answer'(1).
> Has any progress been made in answering this question since then? The
> authors also said, 'Another intriguing question is why evolutionary
> process(es) led to the extant scenario: a genome with a reduced, but
> often similar information content in almost all organisms in spite of a
> great variation in size'.
> To be more specific, I would ask why have the genes coding for
> respiratory enzymes remained in the mitochondrion in most cases instead
> of going to the nucleus?
> 1. Progress in Cell Research, vol. 5, 131-135, (1995), Proceedings of
> the 23rd Bari Meeting on Bioenergetics.
> Andrew Gyles
> Sent via Deja.com http://www.deja.com/
> Before you buy.
> ---

A possible answer to qour question is given in

Race et al. (1999), Trends in Genetics 15 (9), 364-370

In this article the focus is on the persistence of chloroplast genomes but
what is true for plastids should also be true for mitochondria.


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