Hi Thomas -
I've said it before and I'll say it again - in my opinion the best
multiple sequence alignment editor out there is SeqLab in the Accelrys
Wisconsin Package. It allows exactly the type of simultaneous nuc/AA
editing you're talking about. It does not do the nuc aligning
automatically based on the AA alignment, but it's not all that hard to do
it manually and/or there are scripts out there such as Pearson's old
MRTRANS that will. Just my two cents worth . . . .
Cheers - Steve
Steven M. Thompson
A C T G stevet at bio.fsu.edu
\-/ http://bio.fsu.edu/~stevet/cv.html
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