I found in Science issue 31st March 1995 pagg.1907-1908 an interesting
report about Goodman's theory of slower mutation rate in humans. This idea,
long time adversed, found new support by the data of Wen Li, presented in a
Detroit symposium. He looked at non-coding sequences (pseudogenes, introns)
of monkeys (New and Old World) and humans by the relative rate test and
found significantly slower mutation rate for humans. As a non-expert in
evolution but as a molbiologist interested in DNA repair, I would welcome
any comment about the hypothesis (already done by Britten, Science 231
(1986), 1393-1398) that long-lived animals could have more efficient DNA
repair systems than short-lived ones, which seems now to fit with this new
data, but still surprising due to the highly conserved DNA repair
mechanisms in eukaryotes. In general, I would also be interested to know if
these results prompted already to revise the molecular clock model, as
suggested in the article.
Any comment is welcome.
maga at vetbio.unizh.ch