In article <carmean-1212951940130001 at berbee.botany.ubc.ca> carmean at sfu.ca (Dave
>From: carmean at sfu.ca (Dave Carmean)
>Subject: disequilibrium program
>Date: Tue, 12 Dec 1995 19:40:13 -0800
>Is any software available to calculate multilocus gametic linkage
>disquilibria? Weir's 1990 text book 'Genetic Data Analysis' gives a 442
>line Fortran program that looks like it would do the trick, but I'd mangle
>it typing it in and then I'd have to learn Fortran in order to debug it.
1) LINKDIS program by Bill Black can calculate two loci linkage
disquilibria. It is available through anonymous ftp from Bill Black at
1. Log on to the network
2. ftp lamar.colostate.edu
3. <user:> anonymous
4. <password:> your id
5. cd pub/wcb4
You will see a long list of compressed files which include many other
interesting and useful programs and can be transferred and
unzipped using the PKUNZIP program (which is also available at this
site if you don't already have it).
2) Genetic Data Analysis package by Paul O. Lewis and Dmitri Zaykin (Version
1.0 for Windows, November 28, 1995) contains files with programs based on
programs used by Bruce S. Weir in his book Genetic Data Analysis, the second
issue of which will be distributed by Sinauer Assoc., Inc., along with the
computer package in early spring, 1996.
To get this package you have to establish an anonymous ftp session with
onyx.si.edu, go to the directory 'gdaps/gda' and get the files 'gda1d1.exe'
(be sure you are in binary mode) and 'readme.txt'. The readme file contains
directions on how to unpack the archive once you have it on your PC. You
will need the password to unpack the file gda1d1.exe (which is a
self-extracting, password-protected archive). They need volunteer beta
testers. So, if you are seriously interested in this program, contact POL at
lewisp at onyx.si.edu.
Department of Forest Science
Oregon State University, FSL 077
Corvallis, OR 97331-7501, USA
Phone: (503)-737-6564 (off.) or -6562 (lab.)
E-mail: krutovsk at ccmail.orst.edu or rutovskiik at fsl.orst.edu