conservation of intron-exon boundaries

J. David Spafford jspaffor at gpu2.srv.ualberta.ca
Mon Apr 22 11:16:31 EST 1996


I am sequencing a genomic clone of a jellyfish protein and I am finding the
almost identical exon-intron boundary locations as is found in mammals.  On
the other hand, the same gene in Drosophila has only 40% similar exon-intron
boundaries as mammals.  In terms of the coding region, both mammals and
Drosophila have a 70% similarity in sequence with jellyfish.

What does conservation of intron-exon boundaries mean?  Does it mean that
the genes are regulated similarly?

Thanks in advance,

J. David Spafford,
Department of Biological Sciences, University of Alberta
jspaffor at gpu.srv.ualberta.ca



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