A friend of mine would like some pictures of a protein in several
different states of folding/unfolding. She'd really prefer Cytochrome C,
but other proteins would suffice. Otherwise, her needs are very
flexible:
-- Intermediate states may be observed (NMR, etc.) or modelled (according
to some accepted classical/qm simulation model).
-- Pictures may be space-filling, or ribbon diagrams, or etc.
-- Pictures in any unix-friendly format (gif, tiff, ppm, etc.)
In addition to or in lieu of graphics, perhaps there is a database
of partially-folded structures somewhere, akin to the brookhaven pdb
of folded structure coordinate files? I'm curious about this myself.
Last but not least, can anyone recommend offhand a particularly good
paper on some theoretical or empirical aspects of folding that features
a sequence of pictures as described above (especially of Cyt C!) ?
Thanks for any pictures, pointers, or references! If I discover
anything especially interesting, I'd be glad to summarize and repost.
Regards,
Evan
Evan W. Steeg (416) 978-5182 steeg at ai.toronto.edu
Dept of Computer Science steeg at t13.lanl.gov
University of Toronto,
Toronto, Canada M5S 1A4 FAX: (416) 978-1455
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
"We tend to scoff at the beliefs of the ancients.
But we can't scoff at them personally, to their faces,
and this is what annoys me." - Jack Handey
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-
