Announcement and Call for Papers
THE EVOLUTION OF BIOMOLECULAR STRUCTURES
AND THE STRUCTURE OF BIOMOLECULAR EVOLUTION
A Seminar Track in the
Pacific Symposium on Biocomputing
January 3-6, 1996
Ritz Carlton Hotel, Hawaii
All biological macromolecules have an evolutionary origin that is
manifested in essentially every aspect of their biological and
physico-chemical properties. In order to
understand these macromolecules, it is necessary to understand the
relationship between these properties and the evolutionary pressures
that determined form and function.
Information about the evolutionary history can be used to
help predict the characteristics of these macromolecules.
Conversely, these macromolecules encode this evolutionary
heritage, and can provide insight into the
process of molecular evolution.
Possible topics include:
- Role of natural selection and self-organization in biomolecular evolution
- The relationship between sequence and structure evolution
- Structure-based evolutionary reconstruction
- Definition, significance, and evolution of protein cores, loops, and
other conserved motifs
- Evolutionary interpretations of multiple sequence or structure alignments,
including their use in biomolecular structure prediction
- The exon theory of protein structural organization
We welcome papers describing results from a wide range of possible
methodologies, including analyses of the databases of biomolecular
sequences and structures, simple conceptual and computational
evolutionary models, and experimental results.
Current plans are for electronic publication of the papers by the MIT Press,
in both HTML and postscript. People wishing to present posters without
publishing a full paper may submit an abstract. Preregistration for the
conference is required for the inclusion of a paper in the conference
proceedings.
Paper submission deadline: July 27, 1995
Notice to authors: September 11, 1995
Final paper and preregistration deadline: October 2, 1995
Richard A. Goldstein
Chemistry Department
Biophysics Research Division
University of Michigan
Ann Arbor, MI 48109-1055
(313) 763-8013
fax: (313) 747-4865
email: richardg at chem.lsa.umich.edu
Russ B. Altman
Section on Medical Informatics
Stanford University Medical Center, MSOB X-215
Stanford, CA 94305-5479
(415) 723-6979
fax: (415) 725-7944
email: altman at camis.stanford.edu
