From yellowish from gmail.com Sun Mar 25 07:04:44 2007 From: yellowish from gmail.com (Protenger) Date: Sun Mar 25 14:35:56 2007 Subject: [Molecular-modelling] Enthalpy changes of protein through folding pathway Message-ID: <1174824284.043245.236530@y80g2000hsf.googlegroups.com> Hello I have a very simple question. Suppose in a protein folding pathway we have two opposite charged residues seperated by "d" angstrom such that there is a weak interaction between them. We name it state A, so its enthalpy is Ha. As protein conformation changes through folding pathway we suppose "d" decreases, so interaction between charges become stronger. Now we name it State B and its enthalpy as Hb. My simple question is: is Ha>Hb? or Hb>Ha? Thanks