retrograde messengers?

Gillian Denise Sanders gsanders at atbat.Princeton.EDU
Fri Apr 2 22:20:38 EST 1993

Hi. I am currently working on my undergraduate thesis on neural networks and  
mathematical models. I have been using the backpropagation algorithm and have  
noticed several references to its biological impausibility as one main  
disadvatage. I am taking a brain course and our professor mentioned retrograde  
messengers , nitric oxide and"back talking" in methods of learning such as  
classicalical conditioning. To me this would seem to suggest that perhaps the  
backpropagation method is not entirely biologically implausible...does anyone  
have any information about this topic or else any references to papers which  
discuss retrograde messengers and its backward synaptic directions? Thanks in  
advance. Gillian Sanders

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