Dr Thomas Salt smgxt01 at ucl.ac.uk
Wed Mar 31 10:21:00 EST 1993

jharper at ITSA.UCSF.EDU (M. Jane Harper) writes:

>Today in our neuroscience lecture the prof said that peptides and other
>molecules which act as neurotransmitters couldn't get past the blood-
>brain barrier and had to be manufactured within the CNS.  Several of us
>wondered whether this means that all the glutamine within the CNS is
>made within the CNS [by transamination?]... does anyone have any data
>on this?

Glutamine and Glutamate (which is one of  the transmitter amino acids)
are synthetised in individual cells in the CNS.

Tom Salt

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