In article <2oh0ip$1n9d at obelix.uni-muenster.de>, dylan at uni-muenster.de
> I need some informations concerning following keywords, PrP gene structure, species barriers and conformational conversion.
>> Thanks !
Try performing a literature search:
Numerous articles on prions by:
Carlton Gadjusek (typo?) - Nobel laureate
Ian Patterson (lots of scrapie stuff)
some guy Craigh Lazenby??? working at mit on conformation
BTW the hexapeptide repeat prohisglyglygly(somethingelse) in the prion
is very similar to the region in beta-amyloid proglyglygly......... which
is thought to be involved in plaque formation.
Also a protein named ARIA - isolated by G.Fischbach (typo?) has a high
amino acid sequence similarity with prion proteins.
..... Martin Leach Email:leach at mbcrr.harvard.edu
_|____ Dept. of Pharmacology Phone: (617) 638-5323
/ o / Boston Univ. School of Med. Fax: (617) 638-4329
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p.s. try BioMOO (virtual biology on the internet - telnet