Bovine encephalopathy

Martin Leach leach at mbcrr.harvard.edu
Thu Apr 21 11:13:19 EST 1994

In article <R.Burge.54.000B9573 at bay.cc.kcl.ac.uk>, R.Burge at bay.cc.kcl.ac.uk
(Richard Burge) wrote:

> Breaking off at a tangent - just how does one explain how an ingested prion is 
> infectious anyway? I can't see it getting past the stomach, so I would imagine 
> it is getting into the bloodstream somehow. The reactive part of the prion 
> protein is about 27kD, however - does this _really_ get past the BBB?

I believe parts of prion are protease resistant - hence it gets past the


.....          Martin Leach                Email:leach at mbcrr.harvard.edu 
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