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Half-life of endorphins

caudle at irp.nidr.nih.gov caudle at irp.nidr.nih.gov
Mon Nov 7 16:49:17 EST 1994


On 31 Oct 1994 12:03:02 -0500, 
Drmarts  <drmarts at aol.com> wrote:

>Can anyone tell me the half-life of endorphins released in response to
>prolonged (i.e. a few hours) moderate-to-severe pain?
>
>Sherry Marts
>American Health Assistance Foundation

The peptides (endorphins) are degraded within a few seconds.  However, the 
peptides are released by the afferents transmitting the pain information so 
the levels of peptide may remain elevated for as long as the pain persists.

R. Caudle
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Robert M. Caudle                                      "If I had my life to
NAB, NIDR, NIH                                         live over, I'd be a
Bldg. 49, Rm 1A-11                                     plumber."
9000 Rockville Pike                                        A. Einstein
Bethesda, MD 20892

Caudle at yoda.nidr.nih.gov
or
Caudle at irp.nidr.nih.gov
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~



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