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Advert: Research studentship - neurochemistry of ischaemia

Jon Stamford j.stamford at lhmc.ac.uk
Mon Jul 3 07:43:13 EST 1995

A studentship is available (from September 1995) for research leading 
to a Ph.D. in the Neurotransmission Laboratory of the Anaesthetics 
Unit of the London Hospital Medical College.

Cerebral ischaemia is a major cause of permanent debility. 
The objective of this project is to determine the chronology 
of transmitter release events during the early phase of ischaemia 
and to establish the window of therapeutic opportunity using a r
eal-time transmitter measurement method in brain slices. The N
eurotransmission laboratory has established an in vitro 
method to investigate cerebral ischaemia in striatal and cortical 
brain slices that eliminates the haemodynamic considerations
dependency observed in vivo and thus allows neuroprotective effects t
o be characterised independent of haemodynamic phenomena. The 
intention is to establish the sequence of events that occur in 
this phase and thus to elucidate mechanisms that may be amenable t
o pharmacological intervention, particularly by those agents used 
in clinical anaesthesia. The project is under the supervision of 
Dr Jon Stamford.


The successful candidate will be highly motivated and already hold, 
or be expected to receive, at least an upper second in pharmacology,
physiology, biochemistry or a related discipline. Application is b
y submission of full CV and 2 letters of reference, at least one 
from a member of staff of the applicant’s current department.

Further details from:

Mrs S. Stevens, (secretary) Anaesthetics Unit, London Hospital M
edical College, Alexandra Wing, Royal London Hospital, Whitechapel, L
ondon E1 1BB. (Tel: +44 171 377 7725).Or email Dr Jon Stamford 
(j.stamford at lhmc.ac.uk)

Closing date:

31st July 1995

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