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Anything on Creutzfeldt-Jakob Disease

mpalmer msp30
Tue Jul 18 12:58:20 EST 1995

"John T. Robicheau" <Robicheau at DrugInfoNet.Pharm-Epid.Pitt.Edu> wrote:
>>REJQ89A at prodigy.com (Nathan Cohen) wrote:
>>You may call me to discuss...Robert Cohen 201-599-0325...One British
>>farmer got Jacob Cruetzfeldt disease after contracting bovine >spongioform encephalitis directly from his dairy cow.
>>dwarves treated with human GH in the 1950's also contracted this rare >disease...
>Newsflash Mr Cohen! recombinant human growth hormone didn't exist in the
>1950's. Obviously bovine sources were used. That's why the treated
>patients came down with CJ disease. (totally unrelated to the intrinsic
>GH molecule.)
>Why should anyone call YOU to discuss a topic of which you obviously
>know so little?
All patients who have developed CJD after Growth hormone treatment in the USA, UK and France, received cadaveric HUMAN pituitary derived hormones during the 1970's and 80's. Such material was first introduced in 1958. Hormone prepared in this way was contaminated with the infectious agent (Prion) from CJD cadavers. There are now over 60 cases of CJD transmitted in this way.

Dr. Mark S. Palmer
Prion Disease Group,
Dept. of Biochemistry,
St. Mary's Hospital Medical School,
Norfolk Place,
London. W2  1PG

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