In <3vj15r$9cs at curly.cc.emory.edu> libcm at curly.cc.emory.edu (Chris
>>Jean-Francois Avon (jf_avon at citenet.net) wrote:
>>: >just no one to warn him of the dangers and he didn't know that
>: >is a seizure triggering drug, and produced grand mal seizues in lab
>>: Dear Betty, would you please post substantial pharmacological and
>: data on the subject. I am very interested in hearing about it. I
>>Aspartame (Nutrasweet) was originally developed as an experimental
>neurological drug. It's sweetness was an unexpected side effect.
Even your first sentence is incorrect. The sweetness was an unexpected
and serendipitously noticed thing, but it was found in a dipeptide which
was being used in the synthesis of another protein. Nobody ever
intended to use aspartame itself for anything.
> It was a dud as a neurological agent, except that in large doses,
>it causes brain lesions in lab animals.
In a never-published study, allegedly. Not very good evidence.
> Some humans experience neurological problems with reasonably small
>doses of aspartame.
But this is not seen in double-blind studies. Wups. Big deal.