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Lesch-Nyhan question

c_hou at humc.edu c_hou at humc.edu
Thu Feb 29 10:58:17 EST 1996

What is the neurologic mechanism of the self-mutilation in Lesch-Nyhan
syndrome?  What lesion can possibly explain the uncontrollable and seemingly
unconscious self-mutilation while the urge is not wanted by the patient and can
be sometimes suppressed? Does it have anything to do with the accumulation of
uric acid somewhere?

c_hou at afp76.humc.edu

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