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Cs-gluconate; Cs-methanesulfonate

Dennis Churchill dchurchi at acs.ucalgary.ca
Thu Feb 29 18:07:11 EST 1996

Does anyone have any experience using Cs-gluconate, Cs-methanesulfonate, Cs-acetate etc. for 
replacing chloride in pipette solutions for whole-cell recording or know of a paper that discusses 
these in detail. I would like info on the advantages and disadvantages of each and the best ways 
to make up the solutions.

Some recently mentioned that Cs-methanesulfonate does not dissociate well in solution thus not 
making Cs available for blocking potassium currents. Have others found this?

Thanks in advance for any advice on this topic

Dennis Churchill
U of Calgary
dchurchi at acs.ucalgary.ca

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