Glutamate release

Scott L. Schofield sl.schofield at worldnet.att.net
Thu Jan 23 16:59:55 EST 1997

Michael Duggan <michael.duggan at camr.org.uk> wrote:
: We want to measure glutamate release from cultured dorsal root 
: ganglion neurons. We have had some tries with radiolabelled D-Asp 
: and glutamine labelling of the cells, but the results are not as good 
: as we would like them to be (variability in loading, lack of calcium 
: dependence for release etc.).

I was just passing through.

I have seen several studies of the anticonvulsants lamotrigine (Lamictal)
and gabapentin (Neurontin) that assayed glutamate release.  Perhaps
you could find them on Medline and contact the authors.  

- Scott

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