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Theta mechanisms: still asking.

Ron Blue rcb5 at MSN.COM
Mon Apr 26 21:59:59 EST 1999

If my memory is correct neurons use up oxygen when firing and the pet scans
reveal the increase in activity AFTER it has occurred so our pictures would
be positively correlated with neuro activity.  The neurons are most active
when the oxygen levels are low and levels are brought back up to pair AFTER
the activity is all over.  This seems to be related to your question.  Sorry
I do not remember the source.  Mostly likely Science or Nature.
Ron Blue

----- Original Message -----
From: F. Frank LeFever <flefever at ix.netcom.com>
To: <neur-sci at net.bio.net>
Sent: Monday, April 26, 1999 9:22 PM
Subject: Theta mechanisms: still asking.

> OK, folks, you should have your abstracts for SFN postmarked by now
> (well, maybe on west coast you have a few more minutes...).
> How about a little time for my continuing question: what is the basis,
> at a cellular level, for theta seen in various pathological states
> and/or for transient metabolic perturbations? In hyperventilation or in
> TIA, it obviously has SOMETHING to do with oxygen supply to neural
> (and/or gial?) cells, although as I understand it the relationship is
> less than perfect (Ingvaar et al.?).
> But HOW is altered oxygen translated into altered frequency?  (For that
> matter, is it really a continuum or are there some real qualitative
> changes corresponding roughly to conventional delta/theta/alpha
> boundaries?)
> P.S.( I did manage to find a very detailed treatment of generation of
> rhythms by people who should know--authors included Steriade and Gloor,
> I believe--and I'll give it another try, but at first reading it does
> not seem to answer my question.)
> F. Frank LeFever, Ph.D.
> New York Neuropsychology Group

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