Temperature and voltage clamp

BilZ0r BilZ0r at TAKETHISOUThotmail.com
Mon Nov 8 02:53:47 EST 2004

I was talking to a colleague today, who primary studies antiepileptics with 
voltage clamp on voltage sensitive sodium channels expressed in X. Oocytes. 
He told me he does all of his work, I believe, at 15ºC... Does that sound 

Why would he use such a low temperature? So he could see any effects of 
gating more readily? Any ideas?

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