[Neuroscience] Further indirect neuroscientific evidence for CURSES (or primal pain)

Entertained by my own EIMC licenced.to.be.AEVASIVE at fairyland.org
Wed Sep 27 06:22:55 EST 2006

Nature Neuroscience - 9, 1321 - 1329 (2006)
Published online: 10 September 2006; | doi:10.1038/nn1771
Emotional enhancement of memory via amygdala-driven facilitation of rhinal 
Rony Paz, Joe Guillaume Pelletier, Elizabeth P Bauer & Denis Paré
Center for Molecular and Behavioral Neuroscience, Rutgers, The State 
University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, 
Correspondence should be addressed to Denis Paré pare at axon.rutgers.edu or 
Rony Paz rony.paz at gmail.com

Emotions generally facilitate memory, an effect mediated by the basolateral 
amygdala (BLA). To study the underlying mechanisms, we recorded BLA, 
perirhinal and entorhinal neurons during an appetitive trace-conditioning 
task. We focused on the rhinal cortices because they constitute the 
interface between the hippocampus, a mediator of memory consolidation, and 
the neocortex, the storage site of declarative memories. We found that, 
after unexpected rewards, BLA activity increased impulse transmission from 
perirhinal to entorhinal neurons and that this effect decayed as the 
association between conditioned stimuli and rewards was learned. At this 
late phase of learning, the BLA effect occurred when the animals were 
anticipating the reward. By enhancing the processing of sensory cues, the 
BLA-mediated facilitation of rhinal interactions may explain how the 
amygdala promotes memory formation in emotional conditions. 

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