[Neuroscience] Re: gap juntions

Karthik Rajasekaran via neur-sci%40net.bio.net (by kr5z from virginia.edu)
Mon Aug 6 12:05:24 EST 2007

Thank you, and Christian Wilms.

"Bill" <connelly.bill from gmail.com> wrote in message 
news:1186270364.379013.306300 from x40g2000prg.googlegroups.com...
> On Aug 4, 4:26 am, "Karthik Rajasekaran" <k... from virginia.edu> wrote:
>> Hi
>> I am just curious to know if gap junctions can be studied
>> electrophysiologically in a brain slice akin to studying chemical 
>> synapses?
>> Thanks.
>> Karthik
> Absolutely. Paired whole-cell recording is probably the most direct
> way. Large current steps in neuron A, in both hyperpolarizing and
> depolarizing directions induce a similar, but much smaller voltage
> change in neuron B, and of course, from neuron B back to neuron A.
> See:
> http://www.jneurosci.org/cgi/content/full/25/2/291
> You can also use fill neuron A with a dye, and watch it fill
> neighbouring, electrically coupled neurons.

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