Thank you, and Christian Wilms.
Karthik.
"Bill" <connelly.bill from gmail.com> wrote in message
news:1186270364.379013.306300 from x40g2000prg.googlegroups.com...
> On Aug 4, 4:26 am, "Karthik Rajasekaran" <k... from virginia.edu> wrote:
>> Hi
>> I am just curious to know if gap junctions can be studied
>> electrophysiologically in a brain slice akin to studying chemical
>> synapses?
>> Thanks.
>> Karthik
>> Absolutely. Paired whole-cell recording is probably the most direct
> way. Large current steps in neuron A, in both hyperpolarizing and
> depolarizing directions induce a similar, but much smaller voltage
> change in neuron B, and of course, from neuron B back to neuron A.
>> See:
>http://www.jneurosci.org/cgi/content/full/25/2/291>> You can also use fill neuron A with a dye, and watch it fill
> neighbouring, electrically coupled neurons.
>